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ORIGINAL ARTICLE

Orthotopic heart transplantation: experience with 27 cases

Noedir A. G Stolf; Alfredo I Fiorelli; Pedro Carlos P Lemos; Pablo M. A Pomerantzeff; Fábio B Jatene; José Otávio C Auler Júnior; Jorge M. S Pascual; Edmar Bocchi; Lourdes Higushi; Giovanni Bellotti; Fúlvio Pileggi; Adib D Jatene

DOI: 10.1590/S0102-76381987000200006

ABSTRACT

The authors present the innitial experience with 27 patients, submitted to orthotopic heart transplantation, during the period of 23 months (march 85 to february 87), at the Heart Institute, University of São Paulo Medical School. Indications were idiopathic cardiomiopathy in 12 cases (44.5%), ischemic cardiomiopathy in 10 cases (37%), Chagas' cardiomiopathy in 4 cases (14.8%) and rheumatic heart valve disease in 1 case (37%). The early mortality was 37% (1 case), caused by inespecific graft failure long distance hearvesting and the late mortality was 7.4% (2 cases), caused by rejection and infective endocarditis. The 24 surviving patients were (70.3%) in NYHA class I, 1 patient (37%) is in functional class II and 4 patients are in early post-operative period.

RESUMO

Os autores apresentam a experiência de 27 pacientes portadores de cardiomiopatia em fase terminal, que foram submetidos a transplante cardíaco ortotópico, no período de março de 1985 a fevereiro de 1987 (23 meses), no Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo. As principais indicações foram cardiomiopatia dilatada em 12 casos (44,5%), isquêmica em 10 casos (37,08%), chagásica em 4 casos (14,8%) e reumática em 1 caso (3,7%). A mortalidade imediata foi de 3,7% (1 caso), por falência do enxerto, e a tardia, de 7,4% (2 casos), por rejeição e endocardite. Atualmente, 19 pacientes (70,3%) encontram-se em classe funcional I, 1 paciente (3,7%) em classe funcional II e 4 (14,8%) em pós-operatório recente, embora já realizando exercício programado.
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REFERENCES

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