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Non-cardiogenic pulmonary edema after cardiopulmonary bypass

José Otávio C Auler Júnior; Jorge Maurício Stibich Pascual; José Luís Santello; Pablo M. A Pomerantzeff; Roberto Falzoni; Ruy Vaz Gomide do Amaral; Geraldo Verginelli; Adib D Jatene

DOI: 10.1590/S0102-76381986000200009


Non-cardiogenic pulmonary edema is a recently described serious complication which follows heart surgery under cardiopulmonary bypass. The onset of symptoms is rapid, with bronchospasm, sero-hemorrhagic secretion through the airways, and arterial hypotension. Differential diagnosis with left ventricular failure is obtained from the normal or low pressures in the pulmonary circulation. This points out to an increased vascular permeability as the main ethiological agent. The authors report the occurrence of this syndrome in six patients submitted to heart operations under cardiopulmonary bypass and discuss physiopathology, diagnosis, therapy and histopathological findings in patients with lethal evolution.


O edema pulmonar não cardiogênico é uma complicação grave, de conhecimento recente, que se segue a cirurgias cardíacas com circulação extracorpórea. O quadro clínico é de instalação rápida, caracterizando-se, principalmente, por broncoespasmo, secreção sero-hemorrágica pelas vias aéreas e hipotensão arterial. O diagnóstico diferencial com insuficiência ventricular esquerda é realizado pela constatação de pressões normais, ou baixas, em território pulmonar e átrio esquerdo, sugerindo mecanismo de aumento súbito da permeabilidade capilar.Os autores relatam a ocorrência desta síndrome em 6 pacientes submetidos a operações cardíacas com circulação extracorpórea, tecendo considerações sobre os mecanismos fisiopatológicos aventados, meios de diagnóstico, terapêutica adotada, bem como os achados histopatológicos dos pacientes com má evolução.
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